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流行病与卫生统计学硕导 姜晶

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 姜 晶   医学博士、副主任医师,现任科教部副主任、临床流行病学研究中心主任、流行病学与卫生统计专业硕士生导师,专业研究方向为肿瘤流行病学。目前承担医院大型临床科研项目的科研设计、数据库建设管理、数据分析等任务。并在医院建立起符合国际标准、融病例收集、资源保存、患者随访和资料更新为一体的生物样本库和临床资料数据库,建立起开放共享的肝病及消化道肿瘤研究平台。5年来作为项目负责人已获得国家自然科学基金委、科技部、国家教委、吉林省科委等多项科研基金开展消化道肿瘤和病毒性肝炎的流行病学研究工作。已发表40余篇相关论文,其中SCI论文20余篇。                                                                               

                                                                                   

主要成果

1 国家自然科学基金面上项目:微小RNA基因变异和幽门螺杆菌感染相关性胃癌发生、发展和预后关系的研究 2014.01-2017.12  85万元 项目负责人                                        

2国家自然科学基金面上项目:DNA甲基化相关酶基因变异与Hp感染的交互作用对胃癌易感性影响的流行病学研究 2011.01-2013.12   34万元  项目负责人                                           

3十二五国家科技重大专项艾滋病和病毒性肝炎等重大传染病防治子课题:高剂量乙肝疫苗联合免疫球蛋白的乙肝母婴传播阻断效果的研究  2012.09-2015.09  22万元   项目负责人                                                        

4十二五国家科技重大专项艾滋病和病毒性肝炎等重大传染病防治子课题::针对核苷(酸)类药物应答不佳患者的优化联合治疗方案  2012.01-2015.12   29.2万元      项目负责人                                              

5 Jiang J, Jin MS, Kong F, Cao D, Ma HX, Jia Z, Wang YP, Suo J, Cao X. Decreased galectin-9 and increased tim-3 expression are related to poor prognosis in gastric cancer. PLoS One. 2013 Dec 10;8(12):e81799.                                                                  

6 Cao XY, Jia ZF, Jin MS, Cao DH, Kong F, Suo J, Jiang J*.  Serum pepsinogen II is a better diagnostic marker in gastric cancer. World J Gastroenterol. 2012 Dec 28;18(48):7357-61.                                                              

7 Jiang J, Jia ZF, Kong F, Jin MS, Wang YP, Tian S, Suo J, Cao X.  Association of polymorphism of PTPN 11 encoding SHP-2 with gastric atrophy but not gastric cancer in Helicobacter pylori seropositive Chinese population. BMC Gastroenterol. 2012 Jul 12;12:89.                                                              

8 Jiang J, Jia Z, Cao D, Jin MS, Kong F, Suo J, Cao X.  Polymorphisms of the DNA methyltransferase 1 associated with reduced risks of Helicobacter pylori infection and increased risks of gastric atrophy. PLoS One. 2012;7(9):e46058.                                                              

9 Jia Z, Ding Y, Tian S, Niu J, Jiang J*. Test of IL28B polymorphisms in chronic hepatitis C patients treated with PegIFN and ribavirin depends on HCV genotypes: results from a meta-analysis.  PLoS One. 2;7 

(9): e45698.                                                                       

10 Shi X, Pan Y, Wang M, Wang D, Li W, Jiang T, Zhang P, Chi X, Jiang Y, Gao Y, Zhong J, Sun B, Xu D, Jiang J* Niu J*. IL28B genetic variation is associated with spontaneous clearance of hepatitis C virus      

treatment response, serum IL-28B levels in Chinese population. PLoS One. 2012;7(5):e37054.