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内科学博导(消化)高润平

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高润平,男,1958年1月出生,1982年临床医学本科毕业,1990年获白求恩医科大学传染病学硕士学位,1998年获白求恩医科大学病理学博士学位,2004年晋升为教授。现任吉林大学第一医院肝胆胰内科教授、主任医师,博士研究生导师。
联系方式:Email:gao_runping@yahoo.com
办公电话:0431-81715110;Fax: 0431-85612468

学术荣誉:

2010年度被评为吉林大学第一医院优秀研究生导师

社会兼职:

世界华人消化杂志编委,国家留学基金评审专家,长春市医疗事故鉴定专家。

留学经历:

2000-05至2001-05: 英国南安普顿大学附属医院肝病研究所,访问学者   

2001-8至2004-08:美国俄核俄州立大学Wexner研究所,博士后科学家

主要研究方向:

肝脏和胰腺纤维化的发生机制, 主要涉及胰腺星状细胞在胰腺纤维化发生学的作用及机制

教学及科研:

近5年曾承担临床医学本科及7年制内科学主讲。并负责承担国家自然科学基金面上项目3项,已结题2项,目前在研1项。负责承担吉林省科技厅课题2项,现已通过鉴定,获得吉林省科技进步三等奖1项。累计发表医学论文70余篇,其中SCI收录17篇,ISTP收录5篇。指导的研究生论文2009年被吉林省学位委员会评为吉林省优秀硕士论文。

近5年发表的部分论文:

1.Runping Gao, Brigstock DR. Connective tissue growth factor (CCN2) induces c-fos gene activation and cell proliferation through p42/44 MAP kinase (ERK1/2) in primary rat hepatic stellate cells. J of Hepatology 2004; 40(3): 432-439.

2.Runping Gao, Brigstock DR. Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its carboxyl-terminal domain to integrin αvβ3 and heparan sulfate proteoglycan. J. of Biol Chem 2004; 279 (10): 8848-8855.

3. Runping Gao, Brigstock DR.Connective tissue growth factor (CCN2) in rat pancreatic stellate cell function: integrin α5β1 as a novel CCN2 receptor. Gastroenterology 2005; 129:1019-1030.

4. Runping Gao, Brigstock DR . Activation of nuclear factor kappa B (NF-kB) by connective tissue growth factor (CCN2) is involved in sustaining the survival of primary rat hepatic stellate cells. Cell Communication and Signaling  2005; 3:14-21.

5. Runping Gao, Brigstock DR. A novel integrinα 5β1 bingding domain in module 4 connective tissue growth factor (CTGF/CCN2) promote adhesion and migration of activated pancreatic stellate cells. Gut 2006; 55:856-862

6. Gao Runping, Brigstock DR. Connective tissue growth factor hammerhead ribozyme attenuates heman hepatic stellate cell function. World J Gastroenterol 2009; 15(30):3807-3813

7. Ruijuan Zhang, Runping Gao, Yanfang Jiang, Jie Zhu, Junqi Niu. Expression and effects of connective tissue growth factor on human hepatocellular carcinoma. Hepatology 2010; 52(4s): 941

8. Runping Gao, Yahui Liu, Jie Zhu, Rongli Piao. Enhanced expression of connective tissue growth factor (CTGF/CCN2) and its fibrogenic role in human chronic pancreatitis. The American J of Gastroenterology 2011; 106(S2):160

9. Runping Gao, Jie Zhu, Xiujun Zhang, Yahui Liu. Up-regulation of Toll-like Receptor 4 Signaling Pathway in Human Chronic Pancreatitis. The American J of Gastroenterology 2011; 106(S2):162.

10.Rongli Piao, Brigstock DR, Jie Zhu, Manli Zhang, Runping Gao. The clinical significance of connective tissue growth factor in hepatitis B virus-induced hepatic fibrosis. World J Gastroenterol 2012; 18(18):2280-2286

11. Ming Xiu, Ya-Hui Liu, David R Brigstock, Fang-Hui He, Rui-Juan Zhang, Run-Ping Gao. CTGF is overexpressed in human hepatocellular carcinoma and promotes cell invasion and growth. World J of Gastroenterol. 2012; 18(47):7070-7078

12. Fanghui He, Runping Gao, Rongli Piao, Zhenzhen Tian, Kaiyu Zhang.Detection and clinical significance of pancreatic and serum connective tissue growth factor in the assessment of pancreatic fibrosis. The American J of Gastroenterology 2012; 107(Suppl 1): S88: 204

13.Zhenzhen Tian, Runping Gao, Yajun Li, Fanghui He, Kaiyu Zhang.Bacterial Endotoxin: A Trigger Factor for Human Chronic Pancreatitis. The American J of Gastroenterology 2012; 107(Suppl 1): S88: 205

14.Li Sun, Shuhua Wang, Yajun Li, Yongfang Liu, Zhenzhen Tian, Runping Gao.  IgG4-related autoimmune pancreatitis overlapping With Mikulicz’s disease and lymphadenitis: A case report. The American of Gastroenterology.2013;108(S):S66:211.

15.Shuahua Wang, Ming Xiu, Rongli Piao, Runping Gao. A Case Report of Gastric Cancer Complicated with IgG4-Related Disease. The American J of Gastroenterology.2013;108(S):S46:146

16.Li-Mei Qu, Ya-Hui Liu, David R Brigstock, Xiao-Yu Wen, Yong-Fang Liu, Ya-Jun Li, Run-Ping Gao. IgG4-related autoimmune pancreatitis overlapping With Mikulicz’s disease and lymphadenitis: A case report. World J Gastroenterol 2013; 19(48): 9490-9494